About Drug-induced nephrotoxicityCurrent tools for the diagnosis of kidney function involve blood tests, such as blood urea nitrogen and serum creatinine levels, the significant results show only after substantial kidney damage has occurred, the pharmaceutical industry spends significant amounts. Of money, time and effort to detect toxic effects of drugs as early as possible to prevent the progress of such drug candidates into more expensive drug development stages. Since the kidney is one of the primary sites of drug toxicity, early detection of nephrotocxicity in the preclinical phase of drug development is a major unmet need..

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