Clark, M.D., Douglas D. Richman, M.D., Susan J. Little, M.D., and Sunil K. Ahuja, M.D.: Enhanced CD4+ T-Cell Recovery with Earlier HIV-1 Antiretroviral Therapy Human immunodeficiency virus type 1 infection is seen as a a rapid and profound lack of peripheral-blood CD4+ T cells, followed by a spontaneous but transient recovery in CD4+ T-cell counts, the extent and duration which are poorly defined.1,2 Following this transient increase, there is a progressive decline in CD4+ counts.What is this skin condition and how should it be treated? Over a nine-month period, a 24-year-old woman developed an irritable follicular eruption on both lower legs . Examination revealed a series of dark comedone-like lesions, scattered inflamed papules, isolated pustules and postinflammatory hyperpigmentation. Close examination revealed a number of dilated follicular orifices, which were had and crusted associated trapped hairs. The surrounding terminal hairs were orientated obliquely over your skin surface .